OXYCODONE EG LP can induce primary dependence. When used for a long time, a tolerance to the effects sets in and progressively higher dosages may be needed to continue pain relief.
Chronic use of OXYCODONE EG LP may lead to physical dependence and withdrawal syndrome may appear if discontinuation of treatment is sudden. When a patient no longer requires treatment with oxycodone hydrochloride, it is advisable to gradually reduce the dosage in order to avoid withdrawal symptoms.
When used as directed in patients with chronic pain, the risk of developing physical or psychological dependence is markedly reduced and should be weighed against any benefit. Please discuss this with your doctor.
OXYCODONE EG LP is for oral use only. If overinjected (injection into a vein), the tablet excipients (including talc) may cause local tissue destruction (necrosis), changes in lung tissue (pulmonary granulomas) or other serious life-threatening events .
This medication should be avoided in patients with a history of alcohol and drug abuse.
You may develop hormonal changes while taking these tablets. Your doctor may wish to monitor these changes.
Athletes
Athletes’ attention is drawn to the fact that this medicine can induce a positive reaction in tests carried out during doping controls.
The use of OXYCODONE EG LP as a doping agent can prove to be dangerous for health.
Children and teenagers
OXYCODONE EG LP has not been studied in children under 12 years old. Its safety and effectiveness have not been established so its use in children under 12 is not recommended.
Other medicines and OXYCODONE EG LP 10 mg, prolonged-release film-coated tablet
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. If you take these tablets with other medicines, the effect of these tablets or the other medicine may be affected.
The tablets should not be used concomitantly with a monoamine oxidase inhibitor, or if you have taken this type of medicine within the last two weeks (see section 2 “Do not take OXYCODONE EG LP 10 mg, film-coated tablet with sustained release”).
Tell your doctor or pharmacist if you are taking:
Also tell your doctor if you have recently received an anesthetic.
Concomitant use of OXYCODONE STADA and sedative drugs such as benzodiazepines or related drugs increases the risk of drowsiness, difficulty in breathing (respiratory depression), coma and death. Because of these risks, the concomitant use of these drugs should be considered only when there is no other treatment option.
If your doctor prescribes OXYCODONE STADA with sedative medicines, the dose and the duration of the concomitant treatment should be limited by your doctor.
Tell your doctor about any sedative medication you are taking, and strictly follow their dosage recommendations. It is recommended to inform friends or relatives to be alert to the appearance of the symptoms described above. Contact your doctor if you experience such symptoms.
The risk of side effects is increased when taking antidepressants (such as citalopram, duloxetine, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, venlafaxine). These drugs can interact with oxycodone and you may experience symptoms, such as involuntary rhythmic contractions of muscles, including the muscles that control eye movement, restlessness, excessive sweating, tremors, exaggerated reflexes, increased muscle tone, body temperature above 38°C. Contact your doctor if you experience such symptoms.
